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   Articles with "birc6" as a keyword



Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6

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recommendations! Published in 2023 at "Science"

DOI: 10.1126/science.ade8840

Abstract: Certain inhibitor of apoptosis (IAP) family members are sentinel proteins that prevent untimely cell death by inhibiting caspases. Antagonists, including second mitochondria-derived activator of caspases (SMAC), regulate IAPs and drive cell death. Baculoviral IAP repeat-containing… read more here.

Keywords: cell death; smac; ubiquitin ligase; birc6 ... See more keywords

Exploring the Role of the Inhibitor of Apoptosis BIRC6 in Breast Cancer: A Database Analysis.

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recommendations! Published in 2022 at "JCO clinical cancer informatics"

DOI: 10.1200/cci.22.00093

Abstract: PURPOSE The aim of the present work was to investigate the role of apoptosis inhibitor BIRC6 (baculoviral IAP repeat-containing protein 6) in breast cancer (BC), focusing particularly on its involvement in the metastatic cascade. METHODS… read more here.

Keywords: apoptosis; role; ontology; breast cancer ... See more keywords

Immunohistochemical Expression of Baculoviral Inhibitor of Apoptotic Proteins Repeat-Containing Protein in Tumors of Salivary Gland Origin

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recommendations! Published in 2025 at "Journal of Dentistry"

DOI: 10.30476/dentjods.2024.99323.2139

Abstract: Background: Salivary gland tumors (SGTs) include benign and malignant tumors, such as pleomorphic adenoma (PA), mucoepidermoid carcinoma (MEC), and adenoid cystic carcinoma (ACC). Baculoviral inhibitors of apoptotic proteins (BIAPs) repeat-containing protein 6 (BIRC6), is an… read more here.

Keywords: protein; apoptotic proteins; birc6; salivary gland ... See more keywords

Ethyl acetate extract of Knoxia roxburghii (Rubiaceae) down-regulates ECHDC1, CAMK2D, DDB1, UBA6, BIRC6, and HK1 proteins and ameliorates the symptoms of diabetes mellitus

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recommendations! Published in 2025 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2025.1587858

Abstract: Objective To evaluate the effects of Knoxia roxburghii on blood glucose levels in diabetic rats and to investigate its underlying mechanisms of action using proteomics and metabolomics. Methods Streptozotocin (STZ)-induced diabetic rats were treated with… read more here.

Keywords: camk2d; acetate extract; knoxia roxburghii; birc6 ... See more keywords