Synthesis and antikinetoplastid evaluation of bis(benzyl)spermidine derivatives.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2018.02.087
Abstract: This study describes the synthesis and the biological evaluation of twenty-four original bis(benzyl)spermidines. Structural modifications of the polyamine scaffold were performed in order to avoid easily metabolized bonds. Some bis(benzyl)polyamine derivatives have demonstrated promising activity… read more here.
Keywords: synthesis antikinetoplastid; bis benzyl; antikinetoplastid evaluation; evaluation ... See more keywords
Crystal structure of {N 1,N 3-bis[(1-benzyl-1H-1,2,3-triazol-4-yl)methylidene]-2,2-dimethylpropane-1,3-diamine}bis(thiocyanato-ÎșN)iron(II)
Sign Up to like & getrecommendations! Published in 2020 at "Acta Crystallographica Section E: Crystallographic Communications"
DOI: 10.1107/s2056989020012608
Abstract: The title compound shows a cis-arrangement of the thiocyanate anions, while the coordination polyhedron around the iron(II) atom is close to a trigonal prism. read more here.
Keywords: benzyl triazol; structure bis; crystal structure; bis benzyl ... See more keywords