Strain-release arylations for the bis-functionalization of azetidines.
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DOI: 10.1039/d1cc07053c
Abstract: The addition of nucleophilic organometallic species onto in situ generated azabicyclobutanes enables the selective formation of 3-arylated azetidine intermediates through strain-release. Single pot strategies were further developed for the N-arylation of resulting azetidines, employing either… read more here.
Keywords: strain release; release arylations; arylations bis; functionalization azetidines ... See more keywords