Constructing fused bis-isatins from pyrroloindoles using direct oxidation approach and re-visiting indophenine reaction
Sign Up to like & getrecommendations! Published in 2020 at "Polymer"
DOI: 10.1016/j.polymer.2020.123032
Abstract: Abstract Two novel electron accepting bis-isatins, having fused bis-lactam rings have been synthesized from corresponding pyrroloindoles 7 and 14 by one-pot direct oxidation approach involving oxidant NBS with or without co-oxidant TBHP in DMF/CHCl3. Synthesized… read more here.
Keywords: direct oxidation; indophenine reaction; bis isatins; oxidation approach ... See more keywords
Design, Synthesis and Preliminary Antimicrobial Evaluation of N-Alkyl Chain Tethered C-5 Functionalized Bis-Isatins.
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DOI: 10.1039/c7md00434f
Abstract: A series of N-alkyl tethered C-5 functionalized bis-isatins were synthesized and evaluated for antimicrobial activity against pathogenic microorganisms. The preliminary evaluation studies revealed the compound 4t, with an optimal combination of bromo-substituent at the C-5… read more here.
Keywords: alkyl; tethered functionalized; bis isatins; evaluation ... See more keywords