Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans[S]
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Lipid Research"
DOI: 10.1194/jlr.m093351
Abstract: Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and in the circulation.… read more here.
Keywords: mice humans; monoacylglycerol phosphate; bmp; bis monoacylglycerol ... See more keywords
Efficacy increase of lipid nanoparticles in vivo by inclusion of bis(monoacylglycerol)phosphate.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0002
Abstract: Aim: To investigate the effect of incorporating bis(monoacylglycerol)phosphate (BMP) lipid into a lipid nanoparticle and the functional transport of mRNA by the formulated nanoparticles in vivo. Materials & methods: The nanoparticles were prepared from ionizable… read more here.
Keywords: monoacylglycerol phosphate; lipid nanoparticles; nanoparticles vivo; bis monoacylglycerol ... See more keywords