Synthesis, antitumor activity, enzyme assay, DNA binding and molecular docking of Bis-Schiff bases of pyrazoles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-020-02004-y
Abstract: A novel series of Bis -Schiff bases of pyrazoles 9 – 24 were synthesized by the direct condensation of 5-aminopyrazoles 4a – d with dialdehydes 8a – d in ethanol. The newly synthesized Bis -Schiff… read more here.
Keywords: bis schiff; schiff bases; bases pyrazoles; dna ... See more keywords
Three Co(II) complexes with a sexidentate N2O4-donor bis-Schiff base ligand: Synthesis, crystal structures, DFT studies, urease inhibition and molecular docking studies
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.07.077
Abstract: Abstract Three new N2O4-donor bis-Schiff base Co(II) complexes, Co(C36H34N2O8)·2CH3OH (1), Co(C28H34N2O8S2)·H2O (2) and Co(C40H36N4O8)·3CH3OH (3) with distorted octahedral six-coordinate Co(II) centers were synthesized and determined by single crystal X-ray analysis. The X-ray crystallography shows that… read more here.
Keywords: dft studies; bis schiff; donor bis; three complexes ... See more keywords
Synthesis, molecular docking and DFT analysis of novel bis-Schiff base derivatives with thiobarbituric acid for α-glucosidase inhibition assessment
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DOI: 10.1038/s41598-024-54021-z
Abstract: A library of novel bis-Schiff base derivatives based on thiobarbituric acid has been effectively synthesized by multi-step reactions as part of our ongoing pursuit of novel anti-diabetic agents. All these derivatives were subjected to in… read more here.
Keywords: schiff base; dft; base derivatives; thiobarbituric acid ... See more keywords
Synthesis, characterization and corrosion inhibition behavior of 2-aminofluorene bis-Schiff bases in circulating cooling water
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DOI: 10.1039/d0ra01903h
Abstract: In this work, two new bis-Schiff bases, namely 2-bromoisophthalaldehyde-2-aminofluorene (M1) and glutaraldehyde 2-aminofluorene (M2), were synthesized, and their structures were characterized and confirmed by infrared spectroscopy, Fourier transform mass spectrometry and UV-visible spectroscopy. Their corrosion… read more here.
Keywords: schiff bases; corrosion inhibition; inhibition; bis schiff ... See more keywords
Synthesis of α-Naphthalene Acetic Acid Derived Bis-Schiff Bases: In Vitro Cholinesterase Inhibition, Molecular Docking, Dynamics Simulations, Kinetics, and DFT Analysis
Sign Up to like & getrecommendations! Published in 2025 at "Polycyclic Aromatic Compounds"
DOI: 10.1080/10406638.2025.2551791
Abstract: Abstract This study reports the synthesis, characterization by means of spectroscopic techniques (UV, FT-IR,1H-NMR,13C-NMR and mass) and enzyme inhibitory activities (acetyl and butyryl-cholinesterase) of new bis-Schiff bases derived from α-naphthalene acetic acid. Among the synthetic… read more here.
Keywords: molecular docking; schiff bases; naphthalene acetic; acetic acid ... See more keywords
Metal Based Bioactive Nitrogen and Oxygen Donor Mono and Bis Schiff Bases: Design, Synthesis, Spectral Characterization, Computational Analysis and Antibacterial Screening.
Sign Up to like & getrecommendations! Published in 2022 at "Acta chimica Slovenica"
DOI: 10.17344/acsi.2021.7182
Abstract: The scientific interest in developing the advanced metal based compounds to inhibit and control bacterial infections is continuously rising. Keeping in view their pharmacological significance, two new bioactive symmetrical phenylenediamine mono- and bis-Schiff bases, 2-{[(4-aminophenyl)imino]methyl}-6-methoxyphenol… read more here.
Keywords: schiff bases; bis; metal based; metal ... See more keywords
Synthesis, In Vitro α-Glucosidase Inhibitory Activity and Molecular Docking Study of New Benzotriazole-Based Bis-Schiff Base Derivatives
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DOI: 10.3390/ph16010017
Abstract: This study was carried out to synthesize benzotriazole-based bis-Schiff base scaffolds (1–20) and assess them in vitro for α-glucosidase inhibitory potentials. All the synthetics analogs based on benzotriazole-based bis-Schiff base scaffolds were found to display… read more here.
Keywords: glucosidase; based bis; benzotriazole based; bis schiff ... See more keywords
The Influence of the Structure of Several New ortho-Hydroxy-Ketone Derived bis-Schiff Bases on Their Antibacterial and Anti-Inflammatory Activity
Sign Up to like & getrecommendations! Published in 2020 at "Revista De Chimie"
DOI: 10.37358/rc.20.1.7840
Abstract: The article presents some bis-Schiff bases halogenated derivatives of ortho-hydroxy-ketones with great potential for antimicrobial and antiinflammatory activity. The antimicrobial activities of the Schiff bases were tested in comparison with Chloramphenicol, Nystatin, and Ampicillin upon… read more here.
Keywords: anti inflammatory; schiff bases; ortho hydroxy; influence structure ... See more keywords