Solvent, structural, quantum chemical study and antioxidative activity of symmetrical 1-methyl-2,6-bis[2-(substituted phenyl)ethenyl]pyridinium iodides
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-018-1437-5
Abstract: Abstract15 symmetric 1-methyl-2,6-bis[2-(substituted phenyl)ethenyl]pyridinium iodides were synthesized in this work. Their structures were characterized using IR, 1H and 13C NMR, and UV–Vis spectroscopy. DFT calculations indicated that s-trans/s-trans conformation prevail in all compounds. The effects… read more here.
Keywords: phenyl ethenyl; methyl bis; ethenyl pyridinium; bis ... See more keywords
N2,N9-Bis(Substituted benzyl)-β-Carbolineum Bromides as Potential Anticancer Therapeutics: Design, Synthesis, Cytotoxicity, Drug-DNA Intercalation and In-Silico Binding Properties
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DOI: 10.1016/j.molstruc.2021.130771
Abstract: Abstract The present study reports a series of novel N2,N9-bis(substituted benzyl)-β-carbolineum bromides (4a-f) synthesized from L-tryptophan in three steps with excellent yields (>80%). The structures of synthesized compounds 4a-f were confirmed by 1H- and 13C-NMR,… read more here.
Keywords: dna intercalation; bis substituted; carbolineum bromides; benzyl carbolineum ... See more keywords
Palladium-Catalyzed Synthesis of Bis-Substituted Sulfoxonium Ylides.
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DOI: 10.1021/acs.orglett.8b03744
Abstract: The lack of general access to bis-substituted sulfoxonium ylides is addressed by developing a palladium-catalyzed C-H cross-coupling of α-ester sulfoxonium ylides with (hetero)aryl iodides, bromides, and triflates. Three different catalysts have been evaluated. This method… read more here.
Keywords: substituted sulfoxonium; sulfoxonium ylides; palladium catalyzed; sulfoxonium ... See more keywords
Novel (1E,3E,5E)-1,6-bis(Substituted phenyl)hexa-1,3,5-triene Analogs Inhibit Melanogenesis in B16F10 Cells and Zebrafish
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DOI: 10.3390/ijms19041067
Abstract: The present study aimed to evaluate the anti-melanogenic activity of 1,6-diphenyl-1,3,5-hexatriene and its derivatives in B16F10 murine melanoma cells and zebrafish embryos. Twenty five (1E,3E,5E)-1,6-bis(substituted phenyl)hexa-1,3,5-triene analogs were synthesized and their non-cytotoxic effects were predictively… read more here.
Keywords: b16f10; cells zebrafish; phenyl hexa; substituted phenyl ... See more keywords