Chiral C2 -symmetric bis-thioureas as enzyme mimics in enantioselective Michael addition.
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DOI: 10.1002/chir.23438
Abstract: We report herein the synthesis and application of enantiopure C2 -symmetric primary amine-1,3-bis-thiourea organocatalysts in enantioselective conjugate 1,4-Michael addition of carbonyl containing nucleophiles, to nitroalkenes and N-phenylmaleimide, leading to final products in good enantioselectivities (up… read more here.
Keywords: bis; bis thioureas; michael addition; chiral symmetric ... See more keywords
A sustainable strategy for the synthesis of bis-2-iminothiazolidin-4-ones utilizing novel series of asymmetrically substituted bis-thioureas as viable precursors
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DOI: 10.1039/c8ra01253a
Abstract: A novel series of asymmetrically substituted bis-thioureas has been synthesized in an effective pattern via the reaction of diamines with isothiocyanates utilizing the ultrasonic irradiation as a sustainable energy source. This reaction performs well at… read more here.
Keywords: series asymmetrically; novel series; bis thioureas; substituted bis ... See more keywords