Stereoselective synthesis of (Z)-1,3-bis(α,β-unsaturated carbonyl)-isoindolines from aldehydes and phenacyl azides under metal free conditions.
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DOI: 10.1039/d1cc02884g
Abstract: Here in the present manuscript, we report our observation of an unprecedented stereoselective synthesis of 2H-isoindolin-1,3-ylidenes from 2-(formylphenyl)acrylates and phenacylazide in the presence of piperidine. Unlike in our previous findings, in which we accessed 3-keto-isoquinolines… read more here.
Keywords: carbonyl isoindolines; bis unsaturated; stereoselective synthesis; synthesis bis ... See more keywords