Genome mining of cryptic bisabolenes that were biosynthesized by intramembrane terpene synthases from Antrodia cinnamomea
Sign Up to like & getrecommendations! Published in 2023 at "Philosophical Transactions of the Royal Society B: Biological Sciences"
DOI: 10.1098/rstb.2022.0033
Abstract: Terpenoids represent the largest structural family of natural products (NPs) and have various applications in the pharmaceutical, food and fragrance industries. Their diverse scaffolds are generated via a multi-step cyclization cascade of linear isoprene substrates… read more here.
Keywords: antrodia cinnamomea; mining cryptic; genome mining; bisabolene ... See more keywords
Stereochemical investigations on the biosynthesis of achiral (Z)-γ-bisabolene in Cryptosporangium arvum
Sign Up to like & getrecommendations! Published in 2019 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.15.75
Abstract: A newly identified bacterial (Z)-γ-bisabolene synthase was used for investigating the cyclisation mechanism of the sesquiterpene. Since the stereoinformation of both chiral putative intermediates, nerolidyl diphosphate (NPP) and the bisabolyl cation, is lost during formation… read more here.
Keywords: investigations biosynthesis; bisabolene; bisabolene cryptosporangium; stereochemical investigations ... See more keywords