Molecular design, synthesis, and biological evaluation of bisamide derivatives as cyclophilin A inhibitors for HCV treatment.
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DOI: 10.1016/j.ejmech.2019.112031
Abstract: Hepatitis C virus (HCV) is a major cause of end-stage liver diseases. Direct-acting antivirals (DAAs), including inhibitors of nonstructural proteins (NS3/4A protease, NS5A, and NS5B polymerase), represent key components of anti-HCV treatment. However, some DAAs… read more here.
Keywords: design synthesis; bisamide derivatives; molecular design; synthesis biological ... See more keywords
Phenolic and bisamide derivatives from Aglaia odorata and their biological activities.
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DOI: 10.1080/14786419.2022.2162514
Abstract: Three new compounds (1-3), including two bisamide derivatives (1 and 2) and a lignin (3), along with 15 known compounds were isolated from Aglaia odorata. Compound 2 was a pair of enantiomers and successfully resolved… read more here.
Keywords: aglaia odorata; bisamide derivatives; inhibitory; odorata biological ... See more keywords