Investigation of stereoisomeric bisarylethenesulfonic acid esters for discovering potent and selective PTP1B inhibitors.
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DOI: 10.1016/j.ejmech.2018.12.032
Abstract: Protein tyrosine phosphatase 1B (PTP1B) has been considered as a promising therapeutic target for type 2 diabetes mellitus (T2DM) and obesity due to its key regulating effects in insulin signaling and leptin receptor pathways. In… read more here.
Keywords: bisarylethenesulfonic acid; stereoisomeric bisarylethenesulfonic; acid esters; investigation stereoisomeric ... See more keywords