Design, Synthesis, and Biological Evaluation of 2-((4-Bisarylmethyl-piperazin-1-yl)methyl)benzonitrile Derivatives as HCV Entry Inhibitors.
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DOI: 10.1021/acs.jmedchem.1c01637
Abstract: Viral entry inhibitors are absent in hepatitis C virus (HCV) treatment regimens although a dozen direct-acting antiviral (DAA) drugs are available now. Based on a previously identified HCV entry inhibitor L0909, chemical space exploration and… read more here.
Keywords: methyl benzonitrile; entry; bisarylmethyl piperazin; piperazin methyl ... See more keywords