Complete biosynthesis of the bisbenzylisoquinoline alkaloids guattegaumerine and berbamunine in yeast.
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2112520118
Abstract: Benzylisoquinoline alkaloids (BIAs) are a diverse class of medicinal plant natural products. Nearly 500 dimeric bisbenzylisoquinoline alkaloids (bisBIAs), produced by the coupling of two BIA monomers, have been characterized and display a range of pharmacological… read more here.
Keywords: bisbenzylisoquinoline alkaloids; yeast; complete biosynthesis; guattegaumerine berbamunine ... See more keywords
The cytoprotective and anti-cancer potential of bisbenzylisoquinoline alkaloids from Nelumbo nucifera.
Sign Up to like & getrecommendations! Published in 2019 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026619666191116160908
Abstract: Natural product therapy has been gaining therapeutic importance against various diseases including cancer. The failure of chemotherapy due to its associated adverse effects promoted adjunct therapy with natural products. Phytochemicals exert anti-carcinogenic activities through regulation… read more here.
Keywords: nelumbo nucifera; cytoprotective anti; alkaloids nelumbo; bisbenzylisoquinoline alkaloids ... See more keywords