BISC: accurate inference of transcriptional bursting kinetics from single-cell transcriptomic data
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DOI: 10.1093/bib/bbac464
Abstract: Gene expression in mammalian cells is inherently stochastic and mRNAs are synthesized in discrete bursts. Single-cell transcriptomics provides an unprecedented opportunity to explore the transcriptome-wide kinetics of transcriptional bursting. However, current analysis methods provide limited… read more here.
Keywords: bursting; cell; bisc; cell transcriptomic ... See more keywords