Bismuth Porphyrin Antagonizes Cisplatin-Induced Nephrotoxicity via Unexpected Metallothionein-Independent Mechanisms
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DOI: 10.1016/j.isci.2020.101054
Abstract: Summary Cisplatin (CDDP) has been a highly successful anticancer drug in cancer therapy; however, its further application suffers severe nephrotoxicity. Herein, we identify bismuth tetraphenylporphyrinate [Bi(TPP)] as a potent protective agent against CDDP-induced nephrotoxicity. Bi(TPP)… read more here.
Keywords: bismuth porphyrin; metallothionein independent; induced nephrotoxicity; cisplatin ... See more keywords