Articles with "bisoprolol" as a keyword



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Bisoprolol responses (PK/PD) in hypertensive patients: A cytochrome P450 (CYP) 2D6 targeted polymorphism study

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Published in 2020 at "Saudi Journal of Biological Sciences"

DOI: 10.1016/j.sjbs.2020.06.022

Abstract: Background Bisoprolol is an effective β1-adrenergic blocker, an inter-individual genetic variability was recorded in its response. This study aimed at investigating the association of CYP2D6*2A (rs1080985) and CYP2D6*10 (rs1065852) single-nucleotide polymorphism (SNP) with Bisoprolol response… read more here.

Keywords: bisoprolol; bisoprolol responses; study; responses hypertensive ... See more keywords
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Quantitative analysis of two pharmaceutical combinations containing amlodipine with either bisoprolol or candesartan using different UV spectrophotometric methods.

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Published in 2022 at "Journal of AOAC International"

DOI: 10.1093/jaoacint/qsac018

Abstract: BACKGROUND Two fixed-dose combination tablets of amlodipine with bisoprolol and amlodipine with candesartan were recently approved for the treatment of hypertension. OBJECTIVE Three UV spectrophotometric analytical methods were developed for the estimation of the above… read more here.

Keywords: candesartan; method; bisoprolol; amlodipine ... See more keywords
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Population Pharmacokinetic Analysis of Bisoprolol in Patients With Acute Coronary Syndrome

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Published in 2019 at "Journal of Cardiovascular Pharmacology"

DOI: 10.1097/fjc.0000000000000644

Abstract: Abstract: To date, many questions about the extent and cause of pharmacokinetic (PK) variability of even the most widely studied and prescribed &bgr;1-adrenergic receptor blockers, such as metoprolol and bisoprolol, remain unanswered. Given that there… read more here.

Keywords: acute coronary; bisoprolol; population pharmacokinetic; coronary syndrome ... See more keywords
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Effects of trimetazidine in combination with bisoprolol in patients with chronic heart failure and concomitant chronic obstructive pulmonary disease

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Published in 2021 at "Medicine"

DOI: 10.1097/md.0000000000025491

Abstract: Abstract Background: To the best of our knowledge, there is no study that has conducted a review investigating the clinical efficacy and safety of bisoprolol combined with trimetazidine on chronic heart failure (CHF) patients with… read more here.

Keywords: chronic obstructive; bisoprolol; obstructive pulmonary; pulmonary disease ... See more keywords
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Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol

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Published in 2022 at "Pharmacogenomics and Personalized Medicine"

DOI: 10.2147/pgpm.s352719

Abstract: Purpose Bisoprolol is a widely used beta-blocker in patients with cardiovascular diseases. As with other beta-blockers, there is variability in response to bisoprolol, but the underlying reasons for this have not been clearly elucidated. Our… read more here.

Keywords: clearance; region 11p14; pharmacokinetics pharmacodynamics; region ... See more keywords

The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma

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Published in 2022 at "Frontiers in Nutrition"

DOI: 10.3389/fnut.2022.907986

Abstract: Background and Aim Research has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of bisoprolol in rats.… read more here.

Keywords: egcg; pharmacokinetics pharmacodynamics; gavage; egcg bisoprolol ... See more keywords