Bisoprolol responses (PK/PD) in hypertensive patients: A cytochrome P450 (CYP) 2D6 targeted polymorphism study
Sign Up to like & getrecommendations! Published in 2020 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2020.06.022
Abstract: Background Bisoprolol is an effective β1-adrenergic blocker, an inter-individual genetic variability was recorded in its response. This study aimed at investigating the association of CYP2D6*2A (rs1080985) and CYP2D6*10 (rs1065852) single-nucleotide polymorphism (SNP) with Bisoprolol response… read more here.
Keywords: bisoprolol; bisoprolol responses; study; responses hypertensive ... See more keywords
Quantitative analysis of two pharmaceutical combinations containing amlodipine with either bisoprolol or candesartan using different UV spectrophotometric methods.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac018
Abstract: BACKGROUND Two fixed-dose combination tablets of amlodipine with bisoprolol and amlodipine with candesartan were recently approved for the treatment of hypertension. OBJECTIVE Three UV spectrophotometric analytical methods were developed for the estimation of the above… read more here.
Keywords: candesartan; method; bisoprolol; amlodipine ... See more keywords
Population Pharmacokinetic Analysis of Bisoprolol in Patients With Acute Coronary Syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000000644
Abstract: Abstract: To date, many questions about the extent and cause of pharmacokinetic (PK) variability of even the most widely studied and prescribed &bgr;1-adrenergic receptor blockers, such as metoprolol and bisoprolol, remain unanswered. Given that there… read more here.
Keywords: acute coronary; bisoprolol; population pharmacokinetic; coronary syndrome ... See more keywords
Effects of trimetazidine in combination with bisoprolol in patients with chronic heart failure and concomitant chronic obstructive pulmonary disease
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DOI: 10.1097/md.0000000000025491
Abstract: Abstract Background: To the best of our knowledge, there is no study that has conducted a review investigating the clinical efficacy and safety of bisoprolol combined with trimetazidine on chronic heart failure (CHF) patients with… read more here.
Keywords: chronic obstructive; bisoprolol; obstructive pulmonary; pulmonary disease ... See more keywords
Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol
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DOI: 10.2147/pgpm.s352719
Abstract: Purpose Bisoprolol is a widely used beta-blocker in patients with cardiovascular diseases. As with other beta-blockers, there is variability in response to bisoprolol, but the underlying reasons for this have not been clearly elucidated. Our… read more here.
Keywords: clearance; region 11p14; pharmacokinetics pharmacodynamics; region ... See more keywords
The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.907986
Abstract: Background and Aim Research has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of bisoprolol in rats.… read more here.
Keywords: egcg; pharmacokinetics pharmacodynamics; gavage; egcg bisoprolol ... See more keywords