Efficient generation of bispecific IgG antibodies by split intein mediated protein trans-splicing system
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DOI: 10.1038/s41598-017-08641-3
Abstract: Many methods have been developed to produce bispecific antibodies (BsAbs) for industrial application. However, huge challenges still remain in synthesizing whole length BsAbs, including their assembly, stability, immunogenicity, and pharmacodynamics. Here we present for first… read more here.
Keywords: bispecific igg; split intein; protein trans; igg antibodies ... See more keywords