Guiding bispecific monovalent antibody formation through proteolysis of IgG1 single-chain
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DOI: 10.1080/19420862.2016.1277301
Abstract: ABSTRACT We developed an IgG1 domain-tethering approach to guide the correct assembly of 2 light and 2 heavy chains, derived from 2 different antibodies, to form bispecific monovalent antibodies in IgG1 format. We show here… read more here.
Keywords: bispecific monovalent; igg1; formation; monovalent ... See more keywords