Alanine Mutagenesis in the Complementarity Determining Region 3 of the MTB and HIV-1 Peptide-Bispecific T Cell Receptor Beta Chain Affects Ligand Recognition
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00983
Abstract: Mycobacterium tuberculosis/human immunodeficiency virus (MTB/HIV) coinfection presents a special challenge to the prevention and treatment of tuberculosis and HIV/AIDS. Adoptive transfer of high-affinity T cell receptor (TCR) gene-modified T cells against MTB and HIV antigens… read more here.
Keywords: mtb hiv; hiv; cell; bispecific tcr ... See more keywords
Mammalian Display Platform for the Maturation of Bispecific TCR-Based Molecules
Sign Up to like & getrecommendations! Published in 2022 at "Antibodies"
DOI: 10.3390/antib11020034
Abstract: Bispecific T cell receptor (TCR)-based molecules capable of redirecting and activating T cells towards tumor cells represent a novel and promising class of biotherapeutics for the treatment of cancer. Usage of TCRs allows for targeting… read more here.
Keywords: maturation; tcr; display; bispecific ... See more keywords