Moldable Hyaluronan Hydrogel Enabled by Dynamic Metal-Bisphosphonate Coordination Chemistry for Wound Healing.
Sign Up to like & getrecommendations! Published in 2018 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201700973
Abstract: Biomaterial-based regenerative approaches would allow for cost-effective off-the-shelf solution for the treatment of wounds. Hyaluronan (HA)-based hydrogel is one attractive biomaterial candidate because it is involved in natural healing processes, including inflammation, granulation, and reepithelialization.… read more here.
Keywords: wound healing; coordination; dynamic metal; chemistry ... See more keywords
Bisphosphonate Use Is Protective of Radiographic Knee Osteoarthritis Progression Among those With Low Disease Severity and Being Non‐Overweight: Data From the Osteoarthritis Initiative
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4133
Abstract: Antiresorptive medications have been explored for treating knee osteoarthritis (OA); however, little data exist on the effects of today's more potent nitrogen‐containing oral bisphosphonates on radiographic disease‐progression in patients with varying disease‐severity, especially those who… read more here.
Keywords: osteoarthritis; bisphosphonate use; bisphosphonate; knee ... See more keywords
Microstructural volumetric analysis of the jaw following dental implantation under systemic bisphosphonate delivery: An in vivo and ex vivo rat study.
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DOI: 10.1002/jper.20-0547
Abstract: BACKGROUND Due to bisphosphonate medication, dental implantation with a subsequent infection poses a relevant risk factor to suffer from medication-related osteonecrosis of the jaw. This rat study evaluated different implant materials under systemic bisphosphonate delivery… read more here.
Keywords: systemic bisphosphonate; vivo; bisphosphonate; delivery ... See more keywords
Bisphosphonate use after clinical fracture and risk of new fracture
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DOI: 10.1007/s00198-017-4367-7
Abstract: SummaryAmong older adults with a previous fracture, treatment for osteoporosis was initially associated with a higher risk of new fracture. However, the relative risk of new fracture decreased over time, a trend that is consistent… read more here.
Keywords: new fracture; fracture; clinical fracture; bisphosphonate ... See more keywords
Progression of atypical femur stress fracture after discontinuation of bisphosphonate therapy
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DOI: 10.1007/s00198-021-05948-w
Abstract: Atypical femur fracture (AFF) is an uncommon complication of long-term bisphosphonate use, but the risk declines substantially after treatment cessation. We report a case of a 70-year-old woman with osteopenia treated with alendronate for 9… read more here.
Keywords: femur; fracture; bisphosphonate; atypical femur ... See more keywords
An open-label, prospective, observational study of the efficacy of bisphosphonate therapy for painful osteoid osteoma
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DOI: 10.1007/s00330-017-5019-1
Abstract: AbstractObjectivesTo assess the efficacy of bisphosphonate therapy on bone pain in patients with osteoid osteoma (OO) (main objective), and to describe bisphosphonate-induced changes in nidus mineralisation and regional bone-marrow oedema (BMO).MethodsA prospective, observational study was… read more here.
Keywords: efficacy bisphosphonate; bisphosphonate therapy; bisphosphonate; osteoid osteoma ... See more keywords
The effects of ozone application on genotoxic damage and wound healing in bisphosphonate-applied human gingival fibroblast cells
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DOI: 10.1007/s00784-017-2163-6
Abstract: ObjectivesMedication-related osteonecrosis of the jaws (MRONJ) is an extremely therapy-resistant disease involving the jaws especially following bisphosphonate treatment. Bisphosphonates accumulate in bone in concentrations sufficient to be directly toxic to the oral epithelium. Current therapeutic… read more here.
Keywords: wound healing; genotoxic damage; gas plasma; gingival ... See more keywords
Poly(styryl bisphosphonate) nanoparticles with a narrow size distribution: Synthesis, characterization and antibacterial applications
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DOI: 10.1016/j.eurpolymj.2019.04.007
Abstract: Abstract Bacterial resistance to antibiotics is a major challenge in health research. A recent approach to combat this resistance is by interfering with vital bacterial functional systems. Calcium ions play an important role in bacterial… read more here.
Keywords: stbp nps; size distribution; bisphosphonate; poly stbp ... See more keywords
Outcome of revision surgery for bisphosphonate related subtrochanteric fracture non-union following failed intramedullary nailing.
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DOI: 10.1016/j.injury.2020.09.051
Abstract: BACKGROUND Bisphosphonates use is a recognised cause of atypical femur fractures. Intramedullary nailing is the first line of treatment for these fractures, but failure is a common problem due to altered biology, resulting in a… read more here.
Keywords: bisphosphonate; revision surgery; union; non union ... See more keywords
Bisphosphonate Use After Hip Fracture in Older Adults: A Nationwide Retrospective Cohort Study.
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DOI: 10.1016/j.jamda.2016.12.083
Abstract: OBJECTIVES The aim of this study was to investigate the association between bisphosphonate use and the risk of new fracture in a nationwide cohort of individuals with previous hip fractures, with emphasis on individuals above… read more here.
Keywords: risk; fracture; cohort; hip fracture ... See more keywords
Bisphosphonate-Linked TrkB Agonist: Cochlea-Targeted Delivery of a Neurotrophic Agent as a Strategy for the Treatment of Hearing Loss.
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DOI: 10.1021/acs.bioconjchem.8b00022
Abstract: Hearing loss affects more than two-thirds of the elderly population, and more than 17% of all adults in the U.S. Sensorineural hearing loss related to noise exposure or aging is associated with loss of inner… read more here.
Keywords: hearing loss; delivery neurotrophic; bisphosphonate; targeted delivery ... See more keywords