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Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01000
Abstract: The glycolytic enzyme aldolase is an emerging drug target in diseases such as cancer and protozoan infections which are dependent on a hyperglycolytic phenotype to synthesize adenosine 5'-triphosphate and metabolic precursors for biomass production. To…
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Keywords:
aldolase;
inhibitors mammalian;
mammalian glycolytic;
bisphosphonate ... See more keywords