Lipofuscin Granule Bisretinoid Oxidation in the Human Retinal Pigment Epithelium forms Cytotoxic Carbonyls
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DOI: 10.3390/ijms23010222
Abstract: Age-related macular degeneration (AMD) is the primary cause of central blindness among the elderly. AMD is associated with progressive accumulation of lipofuscin granules in retinal pigment epithelium (RPE) cells. Lipofuscin contains bisretinoid fluorophores, which are… read more here.
Keywords: lipofuscin; oxidation; oxidation products; bisretinoid oxidation ... See more keywords