Asymmetric synthesis of highly functionalized tyrosine derivatives for the construction of bistetrahydroisoquinoline alkaloids
Sign Up to like & getrecommendations! Published in 2018 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2018.07.003
Abstract: Abstract A novel and facile synthesis of l -5-hydroxy-2,4-methoxy-3-methylphenylalanine derivatives, which are the key coupling partners for the asymmetric total synthesis of natural bistetrahydroisoquinoline alkaloids, is realized starting from l -tyrosine with 17% overall yield.… read more here.
Keywords: bistetrahydroisoquinoline alkaloids; tyrosine; asymmetric synthesis; synthesis highly ... See more keywords