Potent Inhibition of E. coli DXP Synthase by a gem-Diaryl Bisubstrate Analog
Sign Up to like & getrecommendations! Published in 2024 at "ACS Infectious Diseases"
DOI: 10.1021/acsinfecdis.3c00734
Abstract: New antimicrobial strategies are needed to address pathogen resistance to currently used antibiotics. Bacterial central metabolism is a promising target space for the development of agents that selectively target bacterial pathogens. 1-Deoxy-d-xylulose 5-phosphate synthase (DXPS)… read more here.
Keywords: synthase; dxps; inhibition; bisubstrate analog ... See more keywords