Visualizing Spatial and Stoichiometric Barriers to Bispecific T-cell Engager Efficacy.
Sign Up to like & getrecommendations! Published in 2022 at "Cancer immunology research"
DOI: 10.1158/2326-6066.cir-21-0594
Abstract: Bispecific T-cell engager (BiTE) molecules are biologic T cell-directing immunotherapies. Blinatumomab is approved for treatment of B-cell malignancies, but BiTE molecule development in solid tumors has been more challenging. Here, we employed intravital imaging to… read more here.
Keywords: cell engager; cell; bite molecule; efficacy ... See more keywords