Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.
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DOI: 10.1021/acs.jmedchem.1c00823
Abstract: Transthyretin (TTR) is a causative protein of TTR amyloidosis (ATTR amyloidosis), a general term for diseases characterized by deposition of TTR amyloid fibrils in specific organs. ATTR amyloidosis can be ameliorated by stabilization of the… read more here.
Keywords: bithionol triclabendazole; ttr; drugs bithionol; amyloidosis ... See more keywords