Bivalency in Drosophila embryos is associated with strong inducibility of Polycomb target genes
Sign Up to like & getrecommendations! Published in 2019 at "Fly"
DOI: 10.1080/19336934.2019.1619438
Abstract: ABSTRACT Polycomb group (PcG) and Trithorax group (TrxG) proteins orchestrate development of a multicellular organism by faithfully maintaining cell fate decisions made early in embryogenesis. An important chromatin mark connected to PcG/TrxG regulation is bivalent… read more here.
Keywords: bivalency; polycomb; drosophila embryos; inducibility ... See more keywords
Decoding the function of bivalent chromatin in development and cancer.
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DOI: 10.1101/gr.275736.121
Abstract: Bivalent chromatin is characterized by the simultaneous presence of H3K4me3 and H3K27me3, histone modifications generally associated with transcriptionally active and repressed chromatin, respectively. Prevalent in embryonic stem cells (ESCs), bivalency is postulated to poise/prime lineage-controlling… read more here.
Keywords: bivalent; bivalency; h3k4me3; bivalent chromatin ... See more keywords