Programmable DNA looping using engineered bivalent dCas9 complexes
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DOI: 10.1038/s41467-017-01873-x
Abstract: DNA looping is a ubiquitous and critical feature of gene regulation. Although DNA looping can be efficiently detected, tools to readily manipulate DNA looping are limited. Here we develop CRISPR-based DNA looping reagents for creation… read more here.
Keywords: bivalent dcas9; programmable dna; dna; dcas9 complexes ... See more keywords