BIX‐01294 enhanced chemotherapy effect in gastric cancer by inducing GSDME‐mediated pyroptosis
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DOI: 10.1002/cbin.11395
Abstract: Abstract Adjuvant chemotherapy in combination with surgery is expected to be a curative strategy for gastric cancer. However, drug resistance remains an obstacle in effective chemotherapy. Therefore, understanding the potential mechanisms of chemotherapy induced gastric… read more here.
Keywords: chemotherapy; gastric cancer; pyroptosis; cancer ... See more keywords
Bixin attenuates mechanical allodynia, anxious and depressive-like behaviors associated with experimental diabetes counteracting oxidative stress and glycated hemoglobin
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DOI: 10.1016/j.brainres.2021.147557
Abstract: Neuropathic pain, depression, and anxiety are common comorbidities in diabetic patients, whose pathophysiology involves hyperglycemia-induced increased oxidative stress. Bixin (BIX), an apocarotenoid extracted from the seeds of Bixa orellana, has been used in traditional medicine… read more here.
Keywords: bixin; like behaviors; mechanical allodynia; bix ... See more keywords
Mixed-ligand cobalt, nickel and zinc coordination polymers based on flexible 1,4-bis((1H-imidazol-1-yl)methyl)benzene and rigid carboxylate linkers
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DOI: 10.1016/j.ica.2016.10.007
Abstract: Abstract The mixed-ligand coordination polymers {[Zn(BIX) 2.5 ](NO 3 ) 2 ·5.5H 2 O} n ( 1 ), {[Co(BIX)(HBTC)](BIX) 0.5 ·H 2 O} n ( 4 ), [Ni(BIX) 2 (BDC)(H 2 O)] n ( 5… read more here.
Keywords: topology; coordination polymers; benzene; mixed ligand ... See more keywords
Co(II) and Cd(II) coordination complexes built with 4,5-dichlorophthalic acid and varied N-donor ligands: Synthesis, topology and photoluminescence properties
Sign Up to like & getrecommendations! Published in 2017 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.07.057
Abstract: Abstract Eight new coordination complexes, namely, [Co2(Dcph)2(Him)4] (1), [Co(Dcph)(dmbipy)]n (2), [Co(Dcph)(1,3-bix)]n (3), [M(Dcph)(1,2-bix)]n [M = Co (4) and Cd (5)], [Co2(Dcph)2(4,4′-bibp)(H2O)2]n (6), {[Cd(Dcph)(4,4′-bpy)(H2O)2]·2(H2O)}n (7), {[Cd(Dcph)(1,3-bix)] H2O}n (8) have been synthesized and characterized (H2Dcph = 4,5-Dichlorophthalic acid, Him = imidazole, dmbipy = 5,5′-dimethyl-2,2′-bipiridine, 1,3-bix = 1,3-bis(imidazole-1-ylmethyl)-benzene,… read more here.
Keywords: dichlorophthalic acid; bix; topology; dcph ... See more keywords
BIX-01294 sensitizes renal cancer Caki cells to TRAIL-induced apoptosis through downregulation of survivin expression and upregulation of DR5 expression
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DOI: 10.1038/s41420-018-0035-8
Abstract: BIX-01294 (BIX), a G9a histone methyltransferase inhibitor, has been reported for its anti-proliferative and anticancer activities against various cancer cell lines. In this study, we investigated whether BIX could sensitize TRAIL-mediated apoptosis in various cancer… read more here.
Keywords: apoptosis; induced apoptosis; expression; dr5 ... See more keywords