Prevalence of antibodies against BKPyV subtype I and IV in kidney transplant recipients and in the general Czech population
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25388
Abstract: Active infection with BK polyomavirus (BKPyV) may cause serious complications in transplantation settings. Recently, the level of BKPyV IgG seroreactivity in graft donors has been shown to predict viremia and BKPyV‐associated nephropathy in kidney transplant… read more here.
Keywords: kidney transplant; bkpyv bkpyv; bkpyv subtype; bkpyv ... See more keywords
The prevalence and isolated subtypes of BK polyomavirus reactivation among patients infected with human immunodeficiency virus-1 in southeastern China
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3724-y
Abstract: BK polyomavirus (BKPyV) is an opportunistic infectious pathogen that is associated with hemorrhagic cystitis and nephropathy, mainly in transplant recipients and human immunodeficiency virus 1 (HIV-1) infected patients. However, molecular characterization studies of BKPyV in… read more here.
Keywords: human immunodeficiency; prevalence; southeastern china; reactivation ... See more keywords
Variant morphology and random chromosomal integration of BK polyomavirus in posttransplant urothelial carcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0489-0
Abstract: BK polyomavirus (BKPyV) causes major complications in solid organ transplant recipients but little is known about its role in the development of urothelial carcinoma (UC) during immunosuppression. Immunohistochemistry (IHC) screening for polyomavirus large T antigen… read more here.
Keywords: ltag expressing; integration; morphology; polyomavirus ... See more keywords
Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20180443
Abstract: Low-level BK polyomavirus (BKPyV) shedding is seen in at least 10% of seropositive immunocompetent adults. Moreover, BKPyV infection is highly prevalent amongst immunocompromised populations, yet little is known on its relationship with malignancy. We studied… read more here.
Keywords: occurrence regression; tag; polyomavirus; bkpyv ... See more keywords
BK polyomavirus-specific antibody and T-cell responses in kidney transplantation: update.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000602
Abstract: PURPOSE OF REVIEW BK polyomavirus (BKPyV) has emerged as a significant cause of premature graft failure after kidney transplantation. Without effective antiviral drugs, treatment is based on reducing immunosuppression to regain immune control over BKPyV… read more here.
Keywords: bkpyv dnaemia; kidney transplantation; bkpyv; cell responses ... See more keywords
Immunologic Clearance of a BK Virus-associated Metastatic Renal Allograft Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation"
DOI: 10.1097/tp.0000000000003193
Abstract: Supplemental Digital Content is available in the text. Background. Metastatic carcinoma of a renal allograft is a rare but life threatening event with a difficult clinical management. Recent reports suggested a potential role of BK… read more here.
Keywords: carcinoma; renal allograft; clearance; tumor ... See more keywords
Development and validation of a risk assessment tool for BKPyV Replication in allogeneic stem cell transplant recipients
Sign Up to like & getrecommendations! Published in 2020 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13395
Abstract: BK polymavirus (BKPyV), a member of the family Polyomaviridae, is associated with increased morbidity and mortality in allogeneic stem cell transplant recipients. read more here.
Keywords: stem cell; allogeneic stem; bkpyv; transplant recipients ... See more keywords
Longitudinal monitoring of BKPyV miRNA levels in kidney transplant recipients with BKPyV‐related pathology reflects viral DNA levels and remain high in viremia patients after clearance of viral DNA
Sign Up to like & getrecommendations! Published in 2022 at "Transplant Infectious Disease"
DOI: 10.1111/tid.13927
Abstract: It is unclear whether polyomavirus BK (BKPyV) microribonucleic acid (miRNA) measurement has additional diagnostic and predictive value in kidney transplant recipients (KTR) as compared to current methods of monitoring BKPyV DNA loads. read more here.
Keywords: dna; viral dna; bkpyv; pathology ... See more keywords
Fate of the Urinary Tract Virus BK Human Polyomavirus in Source-Separated Urine
Sign Up to like & getrecommendations! Published in 2018 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.02374-17
Abstract: ABSTRACT Human polyomaviruses are emerging pathogens that infect a large percentage of the human population and are excreted in urine. Consequently, urine that is collected for fertilizer production often has high concentrations of polyomavirus genes.… read more here.
Keywords: source separated; separated urine; fate; polyomavirus ... See more keywords
Are the Polyomaviruses BK and JC Associated with Opportunistic Infections, Graft-versus-Host Disease, or Worse Outcomes in Adult Patients Receiving Their First Allogeneic Stem Cell Transplantation with Low-Dose Alemtuzumab?
Sign Up to like & getrecommendations! Published in 2017 at "Acta Haematologica"
DOI: 10.1159/000468972
Abstract: Background: The association of polyomaviruses BK and JC with other opportunistic infections and graft-versus-host disease (GvHD) in allogeneic stem cell transplantation is controversially discussed. Methods: We conducted a retrospective study of 64 adult patients who… read more here.
Keywords: cell transplantation; disease; stem cell; allogeneic stem ... See more keywords
BK Polyomavirus-specific T cell immune responses in kidney transplant recipients diagnosed with BK Polyomavirus-associated nephropathy
Sign Up to like & getrecommendations! Published in 2019 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-019-4615-x
Abstract: BackgroundAdjustment of immunosuppression is the main therapy for BK polyomavirus (BKPyV)-associated nephropathy (BKPyVAN) after kidney transplantation (KT). Studies of BKPyV-specific T cell immune response are scarce. Here, we investigated BKPyV-specific T cell immunity in KT… read more here.
Keywords: associated nephropathy; specific cell; recipients diagnosed; polyomavirus ... See more keywords