BK polyomavirus-specific antibody and T-cell responses in kidney transplantation: update.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Infectious Diseases"
DOI: 10.1097/qco.0000000000000602
Abstract: PURPOSE OF REVIEW BK polyomavirus (BKPyV) has emerged as a significant cause of premature graft failure after kidney transplantation. Without effective antiviral drugs, treatment is based on reducing immunosuppression to regain immune control over BKPyV… read more here.
Keywords: bkpyv dnaemia; kidney transplantation; bkpyv; cell responses ... See more keywords
A cluster of broadly neutralizing IgG against BK polyomavirus in a repertoire dominated by IgM
Sign Up to like & getrecommendations! Published in 2023 at "Life Science Alliance"
DOI: 10.26508/lsa.202201567
Abstract: FACS sorting of patient B cells with fluorescent BKPyV VLPs, followed by 10xGenomics scRNAseq, generated a large dataset of BKPyV-specific antibody sequences, among which we were able to identify and characterize broadly neutralizing antibodies. The… read more here.
Keywords: bkpyv specific; broadly neutralizing; repertoire; neutralizing igg ... See more keywords
Pretransplantation seroreactivity in kidney donors and recipients as a predictive factor for posttransplant BKPyV-DNAemia
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.929946
Abstract: BK polyomavirus (BKPyV) often reactivates after kidney transplantation, causing BKPyV-associated nephropathy (BKPyVAN) in 1%–10% of cases with a potential detrimental effect on allograft survival. Kidney transplant recipients are regularly screened for BKPyV DNA in plasma.… read more here.
Keywords: bkpyv specific; posttransplant bkpyv; kidney; bkpyv ... See more keywords