Articles with "blacat1" as a keyword



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Yin Yang 1-stimulated long noncoding RNA bladder cancer-associated transcript 1 upregulation facilitates esophageal carcinoma progression via the microRNA-5590-3p/programmed cell death-ligand 1 pathway

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Published in 2022 at "Bioengineered"

DOI: 10.1080/21655979.2022.2061303

Abstract: ABSTRACT Esophageal carcinoma (EC) is a common gastrointestinal malignancy that poses a threat to public health worldwide. Long noncoding RNA (lncRNA) bladder cancer-associated transcript 1 (BLACAT1) exerts a tumorigenic role in several malignant tumors; nevertheless,… read more here.

Keywords: blacat1; cell; long noncoding; esophageal carcinoma ... See more keywords
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Overexpression of the long non-coding RNA BLACAT1 promotes cell proliferation and invasion in colorectal cancer

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Published in 2019 at "Translational Cancer Research"

DOI: 10.21037/tcr.2018.12.26

Abstract: Background Recent evidence demonstrates that the long non-coding RNA (lncRNA) BLACAT1 is associated with the progression and development of various cancers; however, its effect on tumorigenesis of colorectal cancer (CRC) is still poorly understood. The… read more here.

Keywords: cancer; expression; invasion; blacat1 ... See more keywords
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Long Non-coding RNA BLACAT1 Induces Tamoxifen Resistance in Human Breast Cancer by Regulating miR-503/Bcl-2 Axis

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Published in 2020 at "Cancer Management and Research"

DOI: 10.2147/cmar.s239981

Abstract: Introduction At present, drug resistance remains a major obstacle for breast cancer (BCa) patients who receive tamoxifen (TAM) chemotherapy. In this study, we aimed to investigate the functional role of long non-coding RNA BLACAT1 in… read more here.

Keywords: blacat1; mir 503; cancer; resistance ... See more keywords
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Long Non-Coding RNA BLACAT1 in Human Cancers

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Published in 2020 at "OncoTargets and therapy"

DOI: 10.2147/ott.s261461

Abstract: Abstract Long non-coding RNAs (lncRNAs) are a cluster of RNAs with more than 200 nucleotides in length, which lack protein-coding capacity. They are important regulators of numerous cellular processes, including gene transcription, translation, and posttranslational… read more here.

Keywords: blacat1; human cancers; rna blacat1; long non ... See more keywords
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LncRNA-BLACAT1 Facilitates Proliferation, Migration and Aerobic Glycolysis of Pancreatic Cancer Cells by Repressing CDKN1C via EZH2-Induced H3K27me3

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Published in 2020 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2020.539805

Abstract: Objective To investigate the role of lncRNA-BLACAT1 in promoting H3K27 trimethylation of CDKN1C gene by recruiting EZH2 to regulate CCNE on glycolysis and mitochondrial oxidative phosphorylation of pancreatic cancer (PC) cells. Methods Following bioinformatic prediction,… read more here.

Keywords: proliferation migration; glycolysis; blacat1; ezh2 ... See more keywords

LncRNA BLACAT1 is involved in chemoresistance of non‑small cell lung cancer cells by regulating autophagy.

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Published in 2019 at "International journal of oncology"

DOI: 10.3892/ijo.2018.4614

Abstract: The aim of the present study was to determine the effect of the long non‑coding RNA (lncRNA) bladder cancer‑associated transcript 1 (BLACAT1) in chemoresistance of non‑small cell lung cancer (NSCLC) cells. Expression of lncRNA BLACAT1, microRNA… read more here.

Keywords: chemoresistance; blacat1; nsclc cells; ddp resistant ... See more keywords