In vivo neutralization of dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG antibodies
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DOI: 10.1038/s41467-018-06086-4
Abstract: The black mamba (Dendroaspis polylepis) is one of the most feared snake species of the African savanna. It has a potent, fast-acting neurotoxic venom comprised of dendrotoxins and α-neurotoxins associated with high fatality in untreated… read more here.
Keywords: oligoclonal human; igg; dendrotoxin mediated; mediated neurotoxicity ... See more keywords
Selective blockade of Cav1.2 (α1C) versus Cav1.3 (α1D) L-type calcium channels by the black mamba toxin calciseptine
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DOI: 10.1038/s41467-023-43502-w
Abstract: L-type voltage-gated calcium channels are involved in multiple physiological functions. Here the authors identify calciseptine, a toxin purified from black mamba venom, as a selective inhibitor of Ca_v1.2 L-type Ca^2+ channels. L-type voltage-gated calcium channels… read more here.
Keywords: cav1; type; calcium; toxin ... See more keywords