Decarboxylation of indomethacin induced by heat treatment
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DOI: 10.1016/j.ijpharm.2018.04.022
Abstract: ABSTRACT As crystalline indomethacin is heated and subsequently cooled, it transforms into glassy indomethacin. While the original crystals are off‐white in color, the glass becomes blackish‐brown via a yellow intermediate stage. TLC of the components… read more here.
Keywords: hypoxic conditions; indomethacin induced; indomethacin; blackish brown ... See more keywords