Association of Open vs Robot-Assisted Radical Cystectomy With Mortality and Perioperative Outcomes Among Patients With Bladder Cancer in Sweden
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.8959
Abstract: Key Points Question What are the perioperative, safety, and survival outcomes of robot-assisted laparoscopic radical cystectomy (RARC) with intracorporeal urinary diversion compared with open radical cystectomy (ORC)? Findings This cohort study included 3169 patients undergoing… read more here.
Keywords: radical cystectomy; robot assisted; bladder cancer; perioperative outcomes ... See more keywords
Association of 5α-Reductase Inhibitor Prescription With Bladder Cancer Progression in Males in South Korea
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.13667
Abstract: This cohort study examines the risk of all-cause mortality, bladder instillation, and radical cystectomy in older males with filled prescriptions for a 5α-reductase inhibitor 1 year before a bladder cancer (BC) diagnosis. read more here.
Keywords: bladder cancer; bladder; reductase inhibitor;
Association of BCG Vaccine Treatment With Death and Dementia in Patients With Non–Muscle-Invasive Bladder Cancer
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2023.14336
Abstract: Key Points Question Does the BCG vaccine have a protective association with the risk of Alzheimer disease and related dementias (ADRD)? Findings In this cohort study of 6467 patients with non–muscle-invasive bladder cancer, treatment with… read more here.
Keywords: bladder cancer; treatment; bcg vaccine;
Comparison of Costs of Radical Cystectomy vs Trimodal Therapy for Patients With Localized Muscle-Invasive Bladder Cancer.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA surgery"
DOI: 10.1001/jamasurg.2019.1629
Abstract: Importance Earlier studies on the cost of muscle-invasive bladder cancer treatments lack granularity and are limited to 180 days. Objective To compare the 1-year costs associated with trimodal therapy vs radical cystectomy, accounting for survival… read more here.
Keywords: therapy; bladder cancer; trimodal therapy; radical cystectomy ... See more keywords
microRNA‐99a‐5p induces cellular senescence in gemcitabine‐resistant bladder cancer by targeting SMARCD1
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13192
Abstract: Patients with advanced bladder cancer are generally treated with a combination of chemotherapeutics, including gemcitabine, but the effect is limited due to acquisition of drug resistance. Thus, in this study, we investigated the mechanism of… read more here.
Keywords: cellular senescence; gemcitabine; gemcitabine resistant; bladder cancer ... See more keywords
Mutations in gliclazide‐associated genes may predict poor bladder cancer prognosis
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12583
Abstract: In recent years, an increasing number of patients have had diabetes and cancer simultaneously; thus, it is crucial for physicians to select hypoglycemic drugs with the lowest risk of inducing cancer. Gliclazide is a widely… read more here.
Keywords: bladder cancer; analysis; cancer; predict poor ... See more keywords
Analysis of the role of mutations in the KMT2D histone lysine methyltransferase in bladder cancer
Sign Up to like & getrecommendations! Published in 2019 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12600
Abstract: Histone lysine methyltransferases (HMT) comprise a subclass of epigenetic regulators; dysregulation of these enzymes affects gene expression, which may lead to tumorigenesis. Here, we performed an integrated analysis of 50 HMTs in bladder cancer and… read more here.
Keywords: bladder cancer; histone lysine; analysis; bladder ... See more keywords
LMTK3 promotes tumorigenesis in bladder cancer via the ERK/MAPK pathway
Sign Up to like & getrecommendations! Published in 2020 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.12964
Abstract: Lemur tyrosine kinase 3 (LMTK3) is a key member of the serine–threonine tyrosine kinase family. It plays an important role in breast cancer tumorigenesis and progression. However, its biological role in bladder cancer remains elusive.… read more here.
Keywords: bladder cancer; erk mapk; lmtk3; cancer cells ... See more keywords
A non-G-Quadruplex DNA Aptamer Targeting NCL for Diagnosis and Therapy in Bladder Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300791
Abstract: Bladder cancer (BC) is a highly aggressive malignant tumor affecting the urinary system, characterized by metastasis and a poor prognosis that often leads to limited therapeutic success. In this study, we aimed to develop a… read more here.
Keywords: dna aptamer; non quadruplex; bladder cancer; cancer ... See more keywords
Magnetic-Powered Janus Cell Robots Loaded with Oncolytic Adenovirus for Active and Targeted Virotherapy of Bladder Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202201042
Abstract: A unique robotic medical platform is designed by utilizing cell robots as the active "trojan horse" of oncolytic adenovirus (OA), capable of tumor-selective binding and killing. The OA-loaded cell robots are fabricated by entirely modifying… read more here.
Keywords: cell; bladder cancer; cell robots; oncolytic adenovirus ... See more keywords
Integrated Urinalysis Devices Based on Interface‐Engineered Field‐Effect Transistor Biosensors Incorporated With Electronic Circuits
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203224
Abstract: Urinalysis is attractive in non‐invasive early diagnosis of bladder cancer compared with clinical gold standard cystoscopy. However, the trace bladder tumor biomarkers in urine and the particularly complex urine environment pose significant challenges for urinalysis.… read more here.
Keywords: field effect; bladder; device; bladder cancer ... See more keywords