Piezo1/ITGB1 Synergizes With Ca2+/YAP Signaling to Propel Bladder Carcinoma Progression via a Stiffness‐Dependent Positive Feedback Loop
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.71059
Abstract: Emerging evidence implicates mechanotransduction pathways in modulating bladder carcinoma (BLCA) pathogenesis. However, the crosstalk between Piezo1 and integrin β1 (ITGB1) in extracellular matrix (ECM) stiffness‐driven tumorigenesis remains a critical knowledge gap. This study systematically investigates… read more here.
Keywords: bladder carcinoma; piezo1 itgb1; itgb1;
Lymphoepithelioma‐Like Bladder Carcinoma: A Diagnostic and Therapeutic Challenge. Contribution Using a New Case and Review of the Literature
Sign Up to like & getrecommendations! Published in 2017 at "Clinical Genitourinary Cancer"
DOI: 10.1016/j.clgc.2016.12.023
Abstract: Lymphoepithelioma-like urothelial carcinoma is a rare kind of tumor which has only a little information in the literature. The article presents different therapies for the treatment of this rare disease, creating the hypothesis of performing… read more here.
Keywords: literature; lymphoepithelioma like; like bladder; lymphoepithelioma ... See more keywords
Single-cell RNA sequencing identifies potential critical prognostic biomarkers in bladder carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-23975-z
Abstract: To identify genetic markers that can predict the prognosis of bladder carcinoma (BC) patients using single-cell RNA sequencing (scRNA-seq). The RNA-seq data for BC were obtained from the GSA-Human database (HRA000212). Quality control and normalization… read more here.
Keywords: single cell; rna sequencing; rna; cell ... See more keywords
CircMCTP2 (has-circ-0000658) facilitates the proliferation and metastasis of bladder carcinoma through modulating the miR-498/murine double minute-2 axis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2054161
Abstract: ABSTRACT CircMCTP2 is a novel circRNA, which is associated with various kinds of malignant tumors progression, such as gastric cancer. However, the function of circMCTP2 in bladder carcinoma (BC) has no idea. The purpose of… read more here.
Keywords: mir 498; bladder carcinoma; expression; murine double ... See more keywords
In Utero Exposure to 3,3′,4,4′, 5-Pentachlorobiphenyl Dose-Dependently Induces N-butyl-4-(hydroxybutyl) Nitrosamine in Rats With Urinary Bladder Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Toxicologic Pathology"
DOI: 10.1177/01926233211064180
Abstract: Polychlorinated biphenyls (PCBs) are fat-soluble environmental pollutants that can accumulate in adipose tissue or be secreted in milk. N-butyl-4-(hydroxy butyl) (BBN), a rat bladder carcinogen, recruits the host metabolism to yield its ultimate carcinogenic form… read more here.
Keywords: bladder; bladder carcinoma; expression; dose dependently ... See more keywords
Neoadjuvant immunotherapy for muscle invasive urothelial bladder carcinoma: will it change current standards?
Sign Up to like & getrecommendations! Published in 2021 at "Therapeutic Advances in Urology"
DOI: 10.1177/17562872211029779
Abstract: Immunotherapy, in the form of immune checkpoint inhibitors (ICI), has shown activity in metastatic urothelial bladder carcinoma, resulting in the approval of several ICI agents in the first- and second-line settings. This has led to… read more here.
Keywords: bladder carcinoma; muscle invasive; urothelial bladder;
Bladder carcinoma in a bladder diverticulum: a case report
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medical Case Reports"
DOI: 10.1186/s13256-025-05586-4
Abstract: Bladder carcinoma arising within a bladder diverticulum is a rare but significant clinical entity. Owing to the absence of a muscularis propria in the diverticular wall, these tumors have a higher propensity for early invasion… read more here.
Keywords: carcinoma; bladder diverticulum; case; bladder carcinoma ... See more keywords
Microbiota proteomics profiles in muscle-invasive bladder carcinoma related to response to neoadjuvant chemotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2025.43.16_suppl.4589
Abstract: 4589 Background: Muscle-invasive bladder carcinoma (MIBC) poses significant challenges due to high recurrence and mortality rates, coupled with the toxicity of neoadjuvant chemotherapy (NACT). This has driven the search for biomarkers to improve treatment management… read more here.
Keywords: response; muscle invasive; invasive bladder; bladder carcinoma ... See more keywords
TBX3 stimulates proliferation and stem cell self-renewal in bladder carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-496
Abstract: BACKGROUND With the change of people's lifestyle in recent years, bladder carcinoma has been the second leading cause of death for men. Nevertheless, surgical results of bladder carcinoma are unsatisfying with recurrence and distant metastasis.… read more here.
Keywords: bladder carcinoma; cell; cell self; stem ... See more keywords
Identification of key genes and microRNA regulatory network in development and progression of urothelial bladder carcinoma.
Sign Up to like & getrecommendations! Published in 2021 at "Translational andrology and urology"
DOI: 10.21037/tau-20-1124
Abstract: Background Bladder cancer as other cancers contains multiple dynamic alterations in progression. Theoretically, large number of genes participates in cancer progression. In the present study, the interconnections of genesets defined by Gene Set Enrichment Analysis… read more here.
Keywords: bladder cancer; urothelial bladder; progression; bladder carcinoma ... See more keywords
USP21 promotes cell proliferation and metastasis through suppressing EZH2 ubiquitination in bladder carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "OncoTargets and therapy"
DOI: 10.2147/ott.s124795
Abstract: Bladder cancer (BC) is the second most common malignant tumor of the urinary tract in the world. In this study, we found that ubiquitin-specific protease (USP21) was upregulated in BC and the ectopic expression of… read more here.
Keywords: proliferation metastasis; cell proliferation; bladder; metastasis ... See more keywords