Effects of silodosin, a selective alpha‐1A adrenoceptor antagonist, on erectile function in a rat model of partial bladder outlet obstruction
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DOI: 10.1002/nau.23015
Abstract: We investigated the effects of silodosin (selective α1A‐adrenoceptor antagonist) on erectile dysfunction (ED) in a rat model of bladder outlet obstruction. read more here.
Keywords: silodosin selective; effects silodosin; antagonist erectile; rat model ... See more keywords
Male bladder outlet obstruction: Time to re‐evaluate the definition and reconsider our diagnostic pathway? ICI‐RS 2015
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DOI: 10.1002/nau.23178
Abstract: The diagnosis of bladder outlet obstruction (BOO) in the male is dependent on measurements of pressure and flow made during urodynamic studies. The procedure of urodynamics and the indices used to delineate BOO are well… read more here.
Keywords: definition; bladder outlet; outlet obstruction;
Inhibitory effects of silodosin on the bladder mechanosensitive afferent activities and their relation with bladder myogenic contractions in male rats with bladder outlet obstruction
Sign Up to like & getrecommendations! Published in 2018 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.23547
Abstract: We investigated the effects of silodosin, an α1A‐adrenoceptor (AR) antagonist, on bladder function, especially on non‐voiding contractions (NVCs), in a male rat model of bladder outlet obstruction (BOO) by evaluating cystometry (CMG) findings and bladder… read more here.
Keywords: bladder; effects silodosin; outlet obstruction; afferent activities ... See more keywords
The preventive effects of colony‐stimulating factor 1 receptor (CSF‐1R) inhibition on bladder outlet obstruction induced remodeling
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DOI: 10.1002/nau.24896
Abstract: Bladder outlet obstruction (BOO) is a common problem that can affect bladder structure and function. Currently, there is no effective drugs available to prevent BOO‐induced remodeling. Previous reports have demonstrated that the pathogenesis of BOO… read more here.
Keywords: bladder outlet; bladder; outlet obstruction; csf ... See more keywords
Effect of bladder filling volume on detrusor contractility in men with bladder outlet obstruction
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DOI: 10.1002/nau.25113
Abstract: Bladder outlet obstruction alters detrusor contractility, reducing the bladder's ability to respond to large filling with a risk of urinary retention. read more here.
Keywords: bladder outlet; outlet obstruction; detrusor contractility;
The histopathological and pharmacodynamic effects of intradetrusor decorin injected in a rabbit partial bladder outlet obstruction model
Sign Up to like & getrecommendations! Published in 2017 at "International Urology and Nephrology"
DOI: 10.1007/s11255-017-1518-x
Abstract: Purpose To evaluate whether or not the bladder function can be protected by supporting the detrusor with decorin levels during the fibrotic process.MethodsForty-two male rabbits were divided into three main groups, partial bladder outlet obstruction… read more here.
Keywords: bladder; intradetrusor decorin; partial bladder; outlet obstruction ... See more keywords
Suppression of Oxidative Stress of Modified Gongjin-Dan (WSY-1075) in Detrusor Underactivity Rat Model Bladder Outlet Induced by Obstruction
Sign Up to like & getrecommendations! Published in 2017 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-017-2970-1
Abstract: ObjectiveTo investigate the anti-oxidative stress and preventive effect of modified Gongjin-dan (WSY-1075) in a detrusor underactivity rat model.MethodsRats were randomly allocated to three groups: shamoperated (control), bladder outlet obstruction-induced detrusor underactivity (BOO-DU), and BOO-DU with… read more here.
Keywords: obstruction; wsy 1075; wsy; bladder outlet ... See more keywords
Benefits and Harms of Conservative, Pharmacological, and Surgical Management Options for Women with Bladder Outlet Obstruction: A Systematic Review from the European Association of Urology Non-neurogenic Female LUTS Guidelines Panel.
Sign Up to like & getrecommendations! Published in 2021 at "European urology focus"
DOI: 10.1016/j.euf.2021.10.006
Abstract: CONTEXT While the management of bladder outlet obstruction (BOO) in men has been a topic of several systematic reviews and meta-analyses, no such evidence base exists for female BOO. OBJECTIVE The aim of this systematic… read more here.
Keywords: systematic review; outlet obstruction; conservative pharmacological; urology ... See more keywords
Mesenchymal stem cell therapy inhibited inflammatory and profibrotic pathways induced by partial bladder outlet obstruction and prevented high-pressure urine storage.
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DOI: 10.1016/j.jpurol.2019.03.003
Abstract: BACKGROUND Partial bladder outlet obstruction (pBOO) is characterized by an initial inflammatory response that progresses to smooth muscle hypertrophy and fibrosis. Current treatment modalities carry high risk of morbidity. Mesenchymal stem cells (MSCs) are undifferentiated adult… read more here.
Keywords: partial bladder; therapy; bladder outlet; outlet obstruction ... See more keywords
Characteristics of the mechanosensitive bladder afferent activities in relation with microcontractions in male rats with bladder outlet obstruction
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DOI: 10.1038/s41598-017-07898-y
Abstract: We investigated the characteristics of bladder mechanosensitive single-unit afferent activities (SAAs) in rats with a bladder outlet obstruction (BOO) and their relationship with bladder microcontractions. Male Wistar rats were divided into Sham and BOO groups.… read more here.
Keywords: bladder; outlet obstruction; afferent activities; rats bladder ... See more keywords
Identifying occult bladder outlet obstruction in women with detrusor-underactivity-like urodynamic profiles
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DOI: 10.1038/s41598-021-02617-0
Abstract: Voiding dysfunction can result from detrusor underactivity (DU), bladder outlet obstruction (BOO), or both. Conceptually, women with high-pressure low-flow urodynamic profiles are diagnosed with BOO without DU. However, the possibility of BOO is often neglected… read more here.
Keywords: detrusor underactivity; bladder; bladder outlet; boo ... See more keywords