Ganoderma microsporum immunomodulatory protein induces apoptosis and potentiates mitomycin C‐induced apoptosis in urinary bladder urothelial carcinoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26616
Abstract: Current chemotherapy and immunotherapy treatments followed by transurethral resection for urinary bladder urothelial carcinoma (UC) usually suffer from poor prognosis and high recurrence rate. Design and modification of current formulation with the novel adjuvants are… read more here.
Keywords: ganoderma microsporum; apoptosis; bladder urothelial; urothelial carcinoma ... See more keywords
SPAG5 promotes proliferation and suppresses apoptosis in bladder urothelial carcinoma by upregulating Wnt3 via activating the AKT/mTOR pathway and predicts poorer survival
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0223-2
Abstract: Sperm-associated antigen 5 (SPAG5) is involved in various biological processes. However, the roles of SPAG5 in bladder urothelial carcinoma (BUC) are unknown. This study showed that upregulation of SPAG5 was detected frequently in primary BUC… read more here.
Keywords: buc; bladder urothelial; spag5; urothelial carcinoma ... See more keywords
Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1911321116
Abstract: Significance Electronic-cigarette smoke (ECS) is designed to deliver nicotine, and its use is gaining popularity. Previously, we found that ECS induces DNA damage and inhibits DNA repair in the mouse lungs and bladder urothelium. Nicotine… read more here.
Keywords: bladder urothelial; bladder; mice; urothelial hyperplasia ... See more keywords
MP28-19 NOX-DERIVED SUPEROXIDE PRODUCTION IN BLADDER UROTHELIUM: EFFECT OF AGING AND HUMAN STUDY
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Urology"
DOI: 10.1097/ju.0000000000000867.019
Abstract: thoroughly characterize mouse bladder urothelium. METHODS: 18,917 single cells from C57BL/6 mouse bladder urothelium was analyzed by unbiased single-cell RNA sequencing to classify bladder cell types and their underlying functions. RESULTS: Clustering analysis identified 8… read more here.
Keywords: bladder urothelium; urothelial cells; mouse bladder; bladder urothelial ... See more keywords
Serum Cystatin C Level Is Not a Promising Biomarker for Predicting Clinicopathological Characteristics of Bladder Urothelial Tumors
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/2617439
Abstract: The role of cystatin C (Cys-C) in tumorigenesis and progression of bladder urothelial tumors (BUT) is still indefinite. We retrospectively collected the clinical information from the records of 425 BUT patients. Pretreatment serum Cys-C levels… read more here.
Keywords: urothelial tumors; bladder urothelial; level promising; clinicopathological characteristics ... See more keywords
Three Prognostic Biomarkers Correlate with Immune Checkpoint Blockade Response in Bladder Urothelial Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Genomics"
DOI: 10.1155/2022/3342666
Abstract: Aim We aim to develop a signature that could accurately predict prognosis and evaluate the response to immune checkpoint blockade (ICB) in bladder urothelial carcinoma (BLCA). Methods Based on comprehensive analysis of public database, we… read more here.
Keywords: prognosis; immune checkpoint; bladder urothelial; urothelial carcinoma ... See more keywords
KLK6 Functions as an Oncogene and Unfavorable Prognostic Factor in Bladder Urothelial Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/3373851
Abstract: Background Kallikrein-related peptidase 6 (KLK6) has been substantiated as a diagnostic, prognostic, and therapeutic molecular in several cancer types. In our study, we attempt to explore the biological functions of KLK6 in bladder urothelial carcinoma… read more here.
Keywords: bladder urothelial; expression; urothelial carcinoma; klk6 ... See more keywords
Overexpression of miRNA-93-5p Promotes Proliferation and Migration of Bladder Urothelial Carcinoma via Inhibition of KLF9
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/8911343
Abstract: We focused on studying the effects of a key miRNA-mRNA axis in bladder urothelial carcinoma (BUC). Firstly, miRNAs and mRNAs differentially expressed in BUC were analyzed. Clinical information in the TCGA database was used for… read more here.
Keywords: bladder urothelial; overexpression; buc; urothelial carcinoma ... See more keywords
Urinary Exosomal Long Noncoding RNA TERC as a Noninvasive Diagnostic and Prognostic Biomarker for Bladder Urothelial Carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Immunology Research"
DOI: 10.1155/2022/9038808
Abstract: Purpose Bladder cancer is one of the most common urological malignancies worldwide, and approximately 90% of bladder cancer cases are histologically typed as bladder urothelial carcinoma (BLCA). Exosomes are 30 to 200 nm extracellular vesicles that… read more here.
Keywords: bladder urothelial; prognostic biomarker; terc; urinary exosomal ... See more keywords
A novel risk score model based on five angiogenesis-related long non-coding RNAs for bladder urothelial carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Cell International"
DOI: 10.1186/s12935-022-02575-1
Abstract: Background Tumour angiogenesis is an independent risk factor for bladder urothelial carcinoma (BUC) progression, but viable and promising antiangiogenic targets are understudied. Emerging evidence suggests that long non-coding RNAs (lncRNAs) play prominent role in the… read more here.
Keywords: buc; risk; urothelial carcinoma; bladder urothelial ... See more keywords
Genomic analysis of same-patient metachronous upper-tract and bladder urothelial carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.449
Abstract: 449Background: Despite similarities between upper-tract (UTUC) and bladder urothelial carcinoma (BUC), distinctive clinicopathologic and genomic differences are being described. We further investigate the genomic landscape of these two interrelated malignancies in same-patient metachronous (m) UTUC… read more here.
Keywords: buc; patient metachronous; bladder urothelial; upper tract ... See more keywords