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Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02616-22
Abstract: The emergence of carbapenem-resistant Enterobacterales (CRE) that coexpress serine- and metallo-carbapenemases is a severe threat to the efficacy of ceftazidime-avibactam (CZA), which has been proven to be extremely effective against KPC-producing Enterobacterales strains. Our study…
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Keywords:
plasmid;
hybrid plasmid;
klebsiella;
conjugative hybrid ... See more keywords
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Published in 2020 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s262493
Abstract: Introduction Klebsiella pneumoniae carbapenemase (KPC) belongs to the Group-A β-lactamases that incorporate serine at their active site and hydrolyze various penicillins, cephalosporins, and carbapenems. Metallo-beta-lactamases (MBLs) are group-B enzymes that contain one or two essential…
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Keywords:
blavim;
blakpc blaimp;
resistance;
blandm ... See more keywords