Prevalence of ST1049-KL5 carbapenem-resistant Klebsiella pneumoniae with a blaKPC-2 and blaNDM-1 co-carrying hypertransmissible IncM1 plasmid
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DOI: 10.1038/s42003-024-06398-w
Abstract: Infection caused by KPC and NDM carbapenemases co-producing Klebsiella pneumoniae (KPC_NDM_CRKP) poses serious public health concerns. Here, we elucidate the prevalence of a hypertransmissible lncM1 plasmid, pKPC_NDM, co-carrying blaKPC-2 and blaNDM-1 genes in sequence type… read more here.
Keywords: st1049 kl5; pneumoniae; blakpc blandm; plasmid ... See more keywords
Genomic insights into the evolution and mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae co-harboring blaKPC and blaNDM: implications for public health threat mitigation
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DOI: 10.1186/s12941-024-00686-3
Abstract: Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP) co-producing blaKPC and blaNDM poses a serious threat to public health. This study aimed to investigate the mechanisms underlying the resistance and virulence of CR-hvKP isolates collected from a Chinese… read more here.
Keywords: hvkp; pneumoniae; blakpc blandm; plasmid ... See more keywords
Prevalence and Distribution Characteristics of blaKPC-2 and blaNDM-1 Genes in Klebsiella pneumoniae
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DOI: 10.2147/idr.s253631
Abstract: Background Carbapenem-resistant Klebsiella pneumoniae infections have caused major concern and posed a global threat to public health. As blaKPC-2 and blaNDM-1 genes are the most widely reported carbapenem resistant genes in K. pneumonia, it is… read more here.
Keywords: carbapenem resistant; pneumoniae; blandm genes; blakpc blandm ... See more keywords
Genomic characterization of a multidrug-resistant Citrobacter portucalensis isolate co-harboring blaKPC–2 and blaNDM–1 on distinct plasmids
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DOI: 10.3389/fmicb.2025.1633493
Abstract: Background Citrobacter portucalensis is an emerging multidrug-resistant (MDR) pathogen within the Citrobacter genus. Although individual occurrences of blaKPC–2 or blaNDM–1 have been sporadically reported, the coexistence of both carbapenemase genes in a single strain remains… read more here.
Keywords: blakpc blandm; blandm; distinct plasmids; portucalensis ... See more keywords