Blastema formation and periosteal ossification in the regenerating adult mouse digit
Sign Up to like & getrecommendations! Published in 2018 at "Wound Repair and Regeneration"
DOI: 10.1111/wrr.12666
Abstract: While mammals cannot regenerate amputated limbs, mice and humans have regenerative ability restricted to amputations transecting the digit tip, including the terminal phalanx (P3). In mice, the regeneration process is epimorphic and mediated by the… read more here.
Keywords: response; regeneration; formation; bone ... See more keywords
A regeneration-triggered metabolic adaptation is necessary for cell identity transitions and cell cycle re-entry to support blastema formation and bone regeneration
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.76987
Abstract: Regeneration depends on the ability of mature cells at the injury site to respond to injury, generating tissue-specific progenitors that incorporate the blastema and proliferate to reconstitute the original organ architecture. The metabolic microenvironment has… read more here.
Keywords: regeneration; cell; identity; blastema ... See more keywords