Articles with "blastic plasmacytoid" as a keyword



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Heterologous SARS‐CoV‐2 vaccinations in patients with B‐cell lymphoid malignancies

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Published in 2021 at "American Journal of Hematology"

DOI: 10.1002/ajh.26418

Abstract: or decitabine in blast-phase myeloproliferative neoplasm: a multicenter series of 32 consecutive cases. Am J Hematol. 2021;96:781-789. 13. DiNardo CD, Jonas BA, Pullarkat V, et al. Azacitidine and venetoclax in previously untreated acute myeloid leukemia.… read more here.

Keywords: dendritic cell; cell neoplasm; blastic plasmacytoid; plasmacytoid dendritic ... See more keywords
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Blastic plasmacytoid dendritic cell neoplasm (BPDCN): A promising future in the era of targeted therapeutics

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Published in 2022 at "Cancer"

DOI: 10.1002/cncr.34345

Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy arising from precursor dendritic cells. BPDCN cells characteristically express several markers on their cell surfaces including CD123, CD4, and CD56. Because of its rarity… read more here.

Keywords: cell; dendritic cell; plasmacytoid dendritic; treatment ... See more keywords
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Blastic plasmacytoid dendritic cell neoplasm with a history of cytopenia: A case report

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Published in 2020 at "Diagnostic Cytopathology"

DOI: 10.1002/dc.24463

Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy arising from plasmacytoid dendritic cell precursors. The disease typically manifests in the skin, but it also evolves into a leukemic phase or… read more here.

Keywords: case; blastic plasmacytoid; plasmacytoid dendritic; cell neoplasm ... See more keywords
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Molecular Features of Blastic Plasmacytoid Dendritic Cell Neoplasm: DNA Mutations and Epigenetics.

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Published in 2020 at "Hematology/oncology clinics of North America"

DOI: 10.1016/j.hoc.2020.01.002

Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic neoplasm with a dismal prognosis and no standard therapy. In the past, its cellular ontogenesis was obscure, and BPDCN had been erroneously named CD56+/TdT+ blastic NK… read more here.

Keywords: blastic plasmacytoid; molecular features; plasmacytoid dendritic; cell neoplasm ... See more keywords
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Blastic Plasmacytoid Dendritic Cell Neoplasm: The European Perspective.

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Published in 2020 at "Hematology/oncology clinics of North America"

DOI: 10.1016/j.hoc.2020.01.012

Abstract: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) has to be considered an orphan tumoral disease. BPDCN is a good model concerning the structuring and the organization of a concerted medical program on a nation-based, transnational, or… read more here.

Keywords: cell neoplasm; blastic plasmacytoid; plasmacytoid dendritic; dendritic cell ... See more keywords
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Bone marrow clonal hematopoiesis is highly prevalent in blastic plasmacytoid dendritic cell neoplasm and frequently sharing a clonal origin in elderly patients

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Published in 2022 at "Leukemia"

DOI: 10.1038/s41375-022-01538-9

Abstract: Myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML) are reported in up to 20% patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN), where a shared clonal origin is shown in individual case studies. In this… read more here.

Keywords: clonal origin; dendritic cell; blastic plasmacytoid; cell ... See more keywords
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Blastic Plasmacytoid Dendritic Cell Neoplasm Following Acquired Erythropoietic Protoporphyria

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Published in 2017 at "Baylor University Medical Center Proceedings"

DOI: 10.1080/08998280.2017.11930225

Abstract: A 56-year-old Texas rancher with a prior diagnosis of acquired erythropoietic protoporphyria secondary to an underlying myelodysplastic disorder developed an uncommon tumor, blastic plasmacytoid dendritic cell neoplasm (BPDCN). During his initial disease, analysis revealed a… read more here.

Keywords: erythropoietic protoporphyria; blastic plasmacytoid; acquired erythropoietic; plasmacytoid dendritic ... See more keywords
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Evaluating tagraxofusp for the treatment of blastic plasmacytoid dendritic cell neoplasm (BPDCN)

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Published in 2022 at "Expert Opinion on Pharmacotherapy"

DOI: 10.1080/14656566.2022.2029846

Abstract: ABSTRACT Introduction Unique among hematologic malignancies, blastic plasmacytoid dendritic cell neoplasm (BPDCN) affects multiple compartments including bone marrow, hematologic, lymphatic, dermatologic, and central nervous systems (CNS). Treating BPDCN is challenging, historically, as patients display refractoriness… read more here.

Keywords: treatment; dendritic cell; blastic plasmacytoid; cell ... See more keywords
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Tagraxofusp, the first CD123-targeted therapy and first targeted treatment for blastic plasmacytoid dendritic cell neoplasm

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Published in 2019 at "Expert Review of Clinical Pharmacology"

DOI: 10.1080/17512433.2019.1662297

Abstract: ABSTRACT Introduction: CD123 or interleukin 3 receptor alpha is overexpressed in multiple hematologic malignancies. Tagraxofusp is an intravenously administered CD123-directed cytotoxin consisting of the fusion of interleukin-3 with a truncated diphtheria toxin payload and was… read more here.

Keywords: treatment; blastic plasmacytoid; plasmacytoid dendritic; cell neoplasm ... See more keywords
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Patients with blastic plasmacytoid dendritic cell neoplasm in pregnancy: A rare case report

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000030622

Abstract: Rationale: Previous clinical reports of patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN) in pregnancy are rare. Patient concerns: The present study presents the case of 37-year-old women exhibiting third trimester with progressive painless, abdominal… read more here.

Keywords: dendritic cell; plasmacytoid dendritic; patients blastic; pregnancy ... See more keywords
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Pediatric Blastic Plasmacytoid Dendritic Cell Neoplasm: How to Treat?

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Published in 2017 at "Journal of Pediatric Hematology/Oncology"

DOI: 10.1097/mph.0000000000000812

Abstract: To the Editor: We read with great interest the report by Hama et al1 about plasmacytoid dendritic cell leukemia in children. We hereby report our own experience on this extremely rare and aggressive neoplasm. A… read more here.

Keywords: blastic plasmacytoid; plasmacytoid dendritic; cell neoplasm; cell ... See more keywords