Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model.
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DOI: 10.1016/j.ijpharm.2020.119703
Abstract: The purpose of this research was to evaluate a novel long-acting bupivacaine delivery system for control of postoperative pain. Bupivacaine-loaded lipid emulsion (BLE) droplets were created by high-speed homogenization. The BLE droplets were then entrapped… read more here.
Keywords: rat sciatic; ble droplets; bupivacaine loaded; bupivacaine ... See more keywords