Blimp-1 molds the epigenetic architecture of IL-21–mediated autoimmune diseases through an autoregulatory circuit
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DOI: 10.1172/jci.insight.151614
Abstract: Positive regulatory domain 1 (PRDM1) encodes B lymphocyte–induced maturation protein 1 (BLIMP1), also known as a master regulator of T cell homeostasis. We observed a negative relationship between Blimp-1 and IL-21 based on our previous… read more here.
Keywords: blimp molds; il21 promoter; autoimmune diseases; blimp ... See more keywords