Two major clades of blind mole rats (Nannospalax sp.) revealed by mtDNA and microsatellite genotyping in Western and Central Turkey
Sign Up to like & getrecommendations! Published in 2019 at "Mammalian Biology"
DOI: 10.1016/j.mambio.2018.11.004
Abstract: The Anatolian and the Lesser blind mole rats (Nannospalax xanthodon and N. leucodon) are widely distributed in Anatolia and Thrace and feature remarkable diversity of chromosomal races. The evolutionary relationship among various cytotypes has not… read more here.
Keywords: rats nannospalax; two major; western central; microsatellite genotyping ... See more keywords
Transcriptomics and Proteomics Analyses Reveal JAK Signaling and Inflammatory Phenotypes during Cellular Senescence in Blind Mole Rats: The Reflections of Superior Biology
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11091253
Abstract: Simple Summary Blind mole rats (BMR) (Spalax, Nannospalax sp.) are extraordinary organisms with cancer resistance and a long lifespan for their size. Cellular senescence is a condition in which cells cease dividing irreversibly and secrete… read more here.
Keywords: blind mole; cytokine; bmr; senescence ... See more keywords
Damage-Free Shortening of Telomeres Is a Potential Strategy Supporting Blind Mole-Rat Longevity
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14040845
Abstract: Telomere shortening or loss of shelterin components activates DNA damage response (DDR) pathways, leading to a replicative senescence that is usually coupled with a senescence-associated secretory phenotype (SASP). Recent studies suggested that telomere aberration that… read more here.
Keywords: blind mole; longevity; damage; senescence ... See more keywords
Comprehensive Analysis of 13C6 Glucose Fate in the Hypoxia-Tolerant Blind Mole Rat Skin Fibroblasts
Sign Up to like & getrecommendations! Published in 2021 at "Metabolites"
DOI: 10.3390/metabo11110734
Abstract: The bioenergetics of the vast majority of terrestrial mammals evolved to consuming glucose (Glc) for energy production under regular atmosphere (about 21% oxygen). However, some vertebrate species, such as aquatic turtles, seals, naked mole rat,… read more here.
Keywords: hypoxia tolerant; mole rat; spalax cells; blind mole ... See more keywords
Alone, in the dark: The extraordinary neuroethology of the solitary blind mole rat
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.78295
Abstract: On the social scale, the blind mole rat (BMR; Spalax ehrenbergi) is an extreme. It is exceedingly solitary, territorial, and aggressive. BMRs reside underground, in self-excavated tunnels that they rarely leave. They possess specialized sensory… read more here.
Keywords: blind mole; dark extraordinary; extraordinary neuroethology; alone dark ... See more keywords