Genome-Wide CRISPR Off-Target DNA Break Detection by the BLISS Method.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0687-2_15
Abstract: Clustered regularly interspaced palindromic repeat (CRISPR) systems are revolutionizing many areas of biology and medicine, where they are increasingly utilized as therapeutic tools for correcting disease-causing mutations. From a clinical perspective, unintended off-target (OT) DNA… read more here.
Keywords: bliss method; genome wide; target dna; crispr ... See more keywords