LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "blm" as a keyword



Photo by leonhards from unsplash

Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.

Sign Up to like & get
recommendations! Published in 2023 at "Environmental toxicology"

DOI: 10.1002/tox.23824

Abstract: The effect of pachymic acid (PA) on pulmonary fibrosis in rats was expected to be investigated in this study. Firstly, bleomycin (BLM) was used to establish pulmonary fibrosis rat model, then PA (10, 20, or… read more here.

Keywords: lung tissue; blm; pulmonary fibrosis; induced pulmonary ... See more keywords

An improved biotic ligand model (BLM) for predicting Co(II)-toxicity to wheat root elongation: The influences of toxic metal speciation and accompanying ions.

Sign Up to like & get
recommendations! Published in 2019 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2019.109433

Abstract: In order to explore the effects of pH and accompanying ions on divalent cobalt (Co(II)) toxicity to the wheat root elongation, an improved biotic ligand model (BLM) to predict Co(II) toxicity was developed in solution… read more here.

Keywords: toxicity; blm; wheat root; root elongation ... See more keywords

BLM can regulate cataract progression by influencing cell vitality and apoptosis

Sign Up to like & get
recommendations! Published in 2019 at "Experimental Eye Research"

DOI: 10.1016/j.exer.2018.08.022

Abstract: ABSTRACT Age‐related cataract (ARC) is the most common cause of severe visual impairment and blindness. The precise mechanisms of ARC are not completely understood, but it is well accepted that oxidative damage plays an important… read more here.

Keywords: cell vitality; blm; progression; vitality apoptosis ... See more keywords
Photo by leonhards from unsplash

Synergistic protection of Schizandrin B and Glycyrrhizic acid against bleomycin‐induced pulmonary fibrosis by inhibiting TGF‐&bgr;1/Smad2 pathways and overexpression of NOX4

Sign Up to like & get
recommendations! Published in 2017 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2017.04.024

Abstract: Abstract Pulmonary fibrosis, a progressive and lethal lung disease, is a major therapeutic challenge for which new therapeutic strategies are warranted. Schisandrin B (Sch B) and Glycyrrhizic acid (GA) are the principal active ingredients of… read more here.

Keywords: induced pulmonary; pulmonary fibrosis; blm; tgf bgr ... See more keywords
Photo by leonhards from unsplash

Structural Insight into BLM Recognition by TopBP1.

Sign Up to like & get
recommendations! Published in 2017 at "Structure"

DOI: 10.1016/j.str.2017.08.005

Abstract: Topoisomerase IIβ binding protein 1 (TopBP1) is a critical protein-protein interaction hub in DNA replication checkpoint control. It was proposed that TopBP1 BRCT5 interacts with Bloom syndrome helicase (BLM) to regulate genome stability through either… read more here.

Keywords: structural insight; blm recognition; brct5; recognition topbp1 ... See more keywords
Photo by katiemoum from unsplash

Amphiphile-Mediated Ultrasmall Aggregation Induced Emission Dots for Ultrasensitive Fluorescence Biosensing.

Sign Up to like & get
recommendations! Published in 2017 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.7b01797

Abstract: The development of ultrasensitive and highly selective fluorescence biosensors for diverse analytes is highly desirable but remains a challenge. It is attributable to the scarcity of fluorogens with promising brightness, stability, and nontoxicity, which primarily… read more here.

Keywords: fluorescence; aggregation induced; ultrasensitive fluorescence; blm ... See more keywords
Photo by leonhards from unsplash

Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex

Sign Up to like & get
recommendations! Published in 2022 at "Nature Communications"

DOI: 10.1038/s41467-022-28082-5

Abstract: Topoisomerase IIIα is a type 1A topoisomerase that forms a complex with RMI1 and RMI2 called TRR in human cells. TRR plays an essential role in resolving DNA replication and recombination intermediates, often alongside the… read more here.

Keywords: gate; blm; trr; stranded dna ... See more keywords
Photo from wikipedia

Essential involvement of the CX3CL1-CX3CR1 axis in bleomycin-induced pulmonary fibrosis via regulation of fibrocyte and M2 macrophage migration

Sign Up to like & get
recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-17007-8

Abstract: The potential role of macrophages in pulmonary fibrosis (PF) prompted us to evaluate the roles of CX3CR1, a chemokine receptor abundantly expressed in macrophages during bleomycin (BLM)-induced PF. Intratracheal BLM injection induced infiltration of leukocytes… read more here.

Keywords: fibrosis; cx3cr1; essential involvement; involvement cx3cl1 ... See more keywords
Photo by jeisblack from unsplash

Functional conservation of RecQ helicase BLM between humans and Drosophila melanogaster

Sign Up to like & get
recommendations! Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-54101-5

Abstract: RecQ helicases are a family of proteins involved in maintaining genome integrity with functions in DNA repair, recombination, and replication. The human RecQ helicase family consists of five helicases: BLM, WRN, RECQL, RECQL4, and RECQL5.… read more here.

Keywords: functional conservation; recq helicase; drosophila melanogaster; recq ... See more keywords
Photo by leonhards from unsplash

Multi-gram scale synthesis of a bleomycin (BLM) carbohydrate moiety: exploring the antitumor beneficial effect of BLM disaccharide attached to 10-hydroxycamptothecine (10-HCPT)

Sign Up to like & get
recommendations! Published in 2019 at "New Journal of Chemistry"

DOI: 10.1039/c8nj06191b

Abstract: An efficient multi-gram synthesis of bleomycin disaccharide has been developed, and its conjugate with 10-HCPT displayed obvious selectivity, clearly indicating the potential of bleomycin disaccharide in solving the targeted therapy of cytotoxic drugs. read more here.

Keywords: synthesis bleomycin; blm; bleomycin; multi gram ... See more keywords
Photo by hdbernd from unsplash

Effect of Phoenix dactylifera L. Sap Against Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress in Rats: Phytochemical and Therapeutic Assessment

Sign Up to like & get
recommendations! Published in 2019 at "Nutrition and Cancer"

DOI: 10.1080/01635581.2018.1521442

Abstract: Abstract Lung fibrosis is a lethal interstitial disease characterized by massive proliferation of fibroblast inducing excessive collagen deposition. We aimed to investigate whether Date palm sap (DPS) can play a protective effect on bleomycin (BLM)-induced… read more here.

Keywords: fibrosis; dps; sap; effect ... See more keywords