Parthenolide Destabilizes Microtubules by Covalently Modifying Tubulin
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DOI: 10.1016/j.cub.2020.11.055
Abstract: Detyrosination of the α-tubulin C-terminal tail is a post-translational modification (PTM) of microtubules that is key for many biological processes.1 Although detyrosination is the oldest known microtubule PTM,2-7 the carboxypeptidase responsible for this modification, VASH1/2-SVBP,… read more here.
Keywords: parthenolide; vash1 svbp; tubulin; parthenolide destabilizes ... See more keywords