Broad Tricyclic Ring Inhibitors Block SARS-CoV-2 Spike Function Required for Viral Entry
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DOI: 10.1021/acsinfecdis.1c00658
Abstract: The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into host cells requires binding of the viral spike glycoprotein to the angiotensin-converting enzyme 2 (ACE2) receptor, which triggers subsequent conformational changes to facilitate viral… read more here.
Keywords: cov spike; block sars; entry; tricyclic ring ... See more keywords